WSSP-07 Lecture and Lab Files

This web page provides links to materials for the Waksman Student Scholars Program-2007. This information is intended for the students and faculty participating in the program during the 2007 summer and through the 2007-2008 academic year. This material is not intended for general public use and access is password protected. The material on these pages is provided for educational purposes only. Unauthorized use of this material is prohibited. If you wish to download the files or have comments or questions about the material please contact Sue Coletta, Waksman Institute, Rutgers University.

WSSP-07 Lecture notes and figures

Ch.
Topic
Notes (.doc)
Notes (.pdf)
Figures (.ppt)
  Introduction and overview of project     Ch.0.ppt (1.9M)
1
Vectors: Plasmids, Libraries, and Plasmid DNA preps Ch. 1 1.2 M Ch. 1 1.4 M Ch1.ppt (2 M)
2
Restriction enzymes and PCR, Mapping the size of an insert Ch. 2 1.1 M Ch. 2 1.3 M Ch2.ppt (1.3M)
3
DNA Sequencing, Logging onto DSAP Ch. 3 1.1 M Ch. 3 988 K Ch3.ppt (2.2 M)
4
Sequence quality, cropping the ends Ch. 4 2.2 M Ch. 4 1.8 M Ch4.ppt (2.4 M)
5
Editing the waveform Ch. 5 536 K Ch. 5 532 K Ch5.ppt (0.6M)
6
Analysis of XP sequences: determine overlap, contigs Ch. 6 2.2 M Ch. 6 1.8 M Ch6.ppt (1.8M)
7
BLASTN (DNA vs DNA search) Ch. 7 1.1 M Ch. 7 1 M Ch7.ppt (1.1M)
8
BLASTX (Translated DNA vs Protein search) Ch. 8 452 K Ch. 8 288 K Ch8.ppt (0.6M)
9
Determining ORFs, BLASTP (Protein vs Protein search) Ch. 9 688 K Ch. 9 684 K Ch9.ppt (0.4M)
10
Literature Search Ch. 10 2.1 M Ch. 10 2.1 M Ch10.ppt (1.9M)
11
Multiple Sequence alignment and structure analysis Ch. 11 2.3 M Ch. 11 2.2 M Ch11.ppt (XM)
12
Spanning the gap between SP and XP sequences Ch. 12 1.5 M Ch. 12 M 1.7 M Ch12.ppt (2.5 M)
13

Protein analysis, SDS gels, Western Blots

Ch. 13 1.1 M Ch. 13 1.6 M Ch13.ppt (0.9 M)
  GE Background and Principals, Protocols, & Results Background (pdf) Protocols (pdf) Results (ppt)
14
Preparing a poster     Ch14.ppt (4.8M)

WSSP-07 Lab protocols and notes

Lab
Topic .doc File .pdf File (Size)
0
Introduction to the WSSP laboratory Lab 0 (120K) Lab 0 (120K)
1
Pipeting and weighing Lab 1 (360K) Lab 1 (360K)
2
Sterile technique and setting up ON cultures Lab 2 (92K) Lab 2 (92K)
3
Plasmid DNA minipreps Lab 3 (168K) Lab 3 (168K)
4
Restriction enzymes and PCR (Detailed protocol) Lab 4 (92K) Lab 4 (92K)
5
Preparing an agarose gel (Detailed protocol) Lab 5 (40K) Lab 5 (40K)
6
Running an agarose gel Lab 6 (180K) Lab 6 (180K)
7
DNA Sequencing Lab 7 (40K) Lab 7 (40K)
8
Deletion subcloning of a library plasmid Lab 8 (184K) Lab 8 (104K)
9S
HiTrap column chromatography (student protocol) Lab 9 (216K) Lab 9 (424K)
9T
HiTrap column chromatography (teacher protocol) Lab 9 (320K) Lab 9 (452K)
  Recipe for 1X TBE + EtBr (.doc)
Fall 2007 Supply list and instructions for experiments at the schools (.doc)  

Background and Research Literature

Hand SC, Jones D, Menze MA, Witt TL. (2007) Life without water: expression of plant lea genes by an anhydrobiotic arthropod. J. Exp. Zool. 307A:
62–66.

Qiu, Z, Bossier P, Wang X, Bojikova-Fournier S, MacRae TH (2006) Diversity, structure, and expression of the gene for p26, a small heat shock protein from Artemia. Genomics 88: 230–240

Chen, T, Amons, R, Clegg, JS, Warner, AH, MacRae, TH (2003) Molecular characterization of artemin and ferritin
from Artemia franciscana. Eur. J. Biochem. 270, 137–145.

Gilbert Van Stappen, Introduction, biology and ecology of Artemia. http://www.fao.org/DOCREP/003/W3732E/w3732e0m.htm

Editorial on the value of sequencing genomes from divers organisms Nature 2007, 449, page 1

Teacher Links